2023
- Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA–Lipid ComplexesJános Szebeni, et al.ACS Nanodoi: https://doi.org/10.1021/acsnano.2c11904
- Role of anti-polyethylene glycol (PEG) antibodies in the allergic reactions to PEG-containing Covid-19 vaccines: Evidence for immunogenicity of PEGKozma, et al.Vaccinedoi: https://doi.org/10.1016/j.vaccine.2023.06.009
- High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profilerSych, et al.nature biotechnologydoi: https://doi.org/10.1038/s41587-023-01825-5
- Surface display of functional moieties on extracellular vesicles using lipid anchorsZheng, et al.Journal of Controlled Releasedoi: https://doi.org/10.1016/j.jconrel.2023.04.033
- Covid-19 vaccines elicit effective IgG responses in an elderly thymus cancer patient with chemotherapyAkos Koller & János SzebeniHuman Vaccines & Immunotherapeuticsdoi: https://doi.org/10.1080/21645515.2023.2188035
2022
- Cell-specific targeting of extracellular vesicles though engineeringthe glycocalyxZheng, et al.Journal of Extracellular Vesiclesdoi: https://doi.org/10.1002/jev2.12290
- A Bayesian implementation of Quality-by-Design for the development of Cationic Nano-Lipid for siRNA TransfectionBastogne, Thierry, et al.IEEE Transactions on NanoBiosciencedoi: https://doi.org/10.1109/tnb.2022.3213412
- Principles for designing an optimal mRNA lipid nanoparticle vaccineKon, Edo, et al.Current Opinion in Biotechnologydoi: https://doi.org/10.1016/j.copbio.2021.09.016
- Delivery strategies of RNA therapeutics to leukocytesTarab-Ravski, Dana, et al.Journal of Controlled Releasedoi: https://doi.org/10.1016/j.jconrel.2022.01.016
- Nanotechnology-based strategies against SARS-CoV-2 variantsHuang, Xiangang, et al.Nature Nanotechnologydoi: https://doi.org/10.1038/s41565-022-01174-5
- mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cellsBevers, Sanne, et al.Molecular Therapydoi: https://doi.org/10.1016/j.ymthe.2022.07.007
- A state of the art in analytical quality-by-design and perspectives in characterization of nano-enabled medicinal productsBastogne, Thierry, et al.Journal of Pharmaceutical and Biomedical Analysisdoi: https://doi.org/10.1016/j.jpba.2022.114911
- Identification of storage conditions stabilizing extracellular vesicles preparationsGörgens, André, et al.Journal of Extracellular Vesiclesdoi: https://doi.org/10.1002/jev2.12238
- Regulatory guidelines and preclinical tools to study the biodistribution of RNA therapeuticsVervaeke, Pieter, et al.Advanced Drug Delivery Reviewsdoi: https://doi.org/10.1016/j.addr.2022.114236
- Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticlesEvers, Martijn J.W., et al.Journal of Controlled Releasedoi: https://doi.org/10.1016/j.jconrel.2022.01.027
- Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccinesSzebeni, J., et al.Nature Nanotechnologydoi: https://doi.org/10.1038/s41565-022-01071-x
- Anti-PEG antibodies compromise the integrity of PEGylated lipid-based nanoparticles via complementEstapé Senti, Mariona, et al.Journal of Controlled Releasedoi: https://doi.org/10.1016/j.jconrel.2021.11.042
- A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factorDézsi, L., et al.GeroSciencedoi: https://doi.org/10.1007/s11357-021-00495-y
2021
- Complement-mediated hypersensitivity reactions to an amphotericin B-containing lipid complex (Abelcet) in pediatric patients and anesthetized rats: Benefits of slow infusionMilosevits, Gergely, et al.Nanomedicine: Nanotechnology, Biology and Medicinedoi: https://doi.org/10.1016/j.nano.2021.102366
- Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?Vogel, Robert, et al.Journal of Extracellular Vesiclesdoi: https://doi.org/10.1002/jev2.12052
- Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine StormKozma, Gergely Tibor, et al.Frontiers in Immunologydoi: https://doi.org/10.3389/fimmu.2021.642860
2020
- Paving the Road for RNA TherapeuticsDammes, Niels, and Peer, DanTrends in Pharmacological Sciencesdoi: https://doi.org/10.1016/j.tips.2020.08.004
- The Critical Choice of Animal Models in Nanomedicine Safety Assessment: A Lesson Learned From Hemoglobin-Based Oxygen CarriersBedocs, Peter, and Szebeni, JanosFrontiers in Immunologydoi: https://doi.org/10.3389/fimmu.2020.584966
- Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imagingGupta, Dhana, et al.Journal of Extracellular Vesiclesdoi: http://dx.doi.org/10.1080/20013078.2020.1800222
- Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticalsKozma, Gergely TiborAdvanced Drug Delivery Reviewsdoi: https://doi.org/10.1016/j.addr.2020.07.024
- Extracellular vesicles as drug delivery systems: Why and how?Elsharkasy, Omnia M., et al.Advanced Drug Delivery Reviewsdoi: https://doi.org/10.1016/j.addr.2020.04.004
- The Biomolecular Corona of Lipid Nanoparticles for Gene TherapyFrancia, Valentina, et al.Bioconjugate Chemistrydoi: https://doi.org/10.1021/acs.bioconjchem.0c00366